List of chemotherapy regimens

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Overview

Chemotherapy regimens are often identified with acronyms, identifying the agents used in combination. Unfortunately, the letters used are not consistent across regimens, and in some cases (for example, "BEACOPP") the same letter is used to represent two different treatments. Because of this, there is not a naming standard for chemotherapy regimens, and this page merely represents commonly used conventions.

The term "Induction regimens" refers to a chemotherapy regimen which is used for the initial treatment of a disease.

Name	Components	Example of uses, and other notes
ABVD ^[1]	Adriamycin, bleomycin, vinblastine, dacarbazine	Hodgkin's lymphoma
ABVE-PC ^[2]	Doxorubicin, bleomycin, vincristine, etoposide, prednisone, cyclophosphamide	Pediatric Hodgkin's lymphoma
AC	Adriamycin/Doxorubicin, Cyclophosphamide	Breast cancer
BEACOPP ^[3]	Bleomycin, etoposide, Adriamycin (doxorubicin), cyclophosphamide, Oncovin (vincristine), procarbazine, prednisone	Hodgkin's lymphoma
BEP	Bleomycin, etoposide, platinum (cisplatin)	Testicular cancer, germ cell tumors
CAF	Cyclophosphamide, Adriamycin/Doxorubicin, 5-FU/Fluorouracil	Breast cancer
CAV	Cyclophosphamide, Adriamycin/Doxorubicin, Vincristine	Lung cancer
CHOP	Cyclophosphamide, doxorubicin (hydroxydoxorubicin), vincristine (Oncovin), prednisone	Non-Hodgkin lymphoma
CHOP-R	CHOP + rituximab	B cell non-Hodgkin lymphoma
COP or CVP	Cyclophosphamide, vincristine (Oncovin), and prednisone	Non-Hodgkin lymphoma in patients with history of cardiovascular disease
CMF	Cyclophosphamide, Methotrexate, and 5-Fluorouracil	Breast Cancer
COPP	Cyclophosphamide, Oncovin (vincristine), procarbazine and prednisone	Non-Hodgkin lymphoma
DA-EPOCH ^[4]	Dose-adjusted Etopiside, prednisone, vincristine (Oncovin), Cyclophosphamide and doxorubicin	Newly diagnosed, aggressive non-Hodgkin lymphoma
DHAP ^[5]	Dexamethasone, cytarabine (high-dose ARA-C), cisplatin	Recurrent or refractory non-Hodgkin lymphoma
EC	Epirubicin, Cyclophosphamide	Breast cancer
ECF	Epirubicin, cisplatin, fluorouracil	Gastric cancer and oesophageal cancer
ESHAP	Etopiside, methylprednisolone (Solu-medrol), cytarabine (ARA-C), cisplatin	Relapsed or refractory non-Hodgkin lymphoma
FN-D ^[6]	Fludarabine, mitoxantrone (Novantrone), dexamethasone	Recurrent or refractory indolent non-Hodgkin lymphoma
FOLFOX	Fluorouracil, leucovorin (folinic acid), and oxaliplatin	Colorectal cancer
HYPER-CVAD ^[7]	Hyperfractionated cyclophosphamide, vincristine (Oncovin), doxorubicin (Adriamycin), dexamethasone (Decadron)	Burkitt's lymphoma
ICE ^[8]'	Ifosfamide, carboplatin, etopiside	Relapsed or primary refractory non-Hodgkin lymphoma
ICE-R	ICE + rituximab	Relapsed or primary refractory non-Hodgkin lymphoma
m-BACOD	Methotrexate, bleomycin, doxorubicin (Adriamycin), cyclophosphamide, vincristine (Oncovin), dexamethasone (Decadron)	Non-Hodgkin lymphoma
MACOP-B ^[9]	Methotrexate, leucovorin, doxorubicin (Adriamycin), cyclophosphamide, vincristine (Oncovin), prednisone, bleomycin	Non-Hodgkin lymphoma
MOPP	Mechlorethamine, vincristine (oncovin), procarbazine, prednisone	Hodgkin's lymphoma
NABTT ^[10]	Methotrexate, calcium leucovorin; methotrexate, calcium leucovorin; methotrexate, calcium leucovorin	Primary CNS lymphoma
PCV	Procarbazine, lomustine (CCNU), vincristine	Brain tumors
ProMACE-MOPP	Methotrexate, doxorubicin (Adriamycin), cyclophosphamide, etoposide + MOPP	Non-Hodgkin lymphoma
ProMACE-CytaBOM	Prednisone, doxorubicin (adriamycin), cyclophosphamide, etoposide, cytarabine, bleomycin, vincristine (Oncovin), methotrexate, leucovorin	Non-Hodgkin lymphoma
R-FCM	Rituximab, fludarabine, cyclophosphamide, mitoxantrone	B cell non-Hodgkin lymphoma
RTOG 93-10 ^[11]	Methotrexate, Leucovorin, vincristine, procarbazine, methotrexate, Leucovorin	Primary CNS lymphoma
Stanford V ^[12]	Doxorubicin (Adriamycin), mechlorethamine, bleomycin, vinblastine, vincristine (Oncovin), etoposide (VP-16), prednisone	Hodgkin's lymphoma
Thal/Dex	Thalidomide, dexamethasone	Multiple myeloma
VAD	Vincristine, Adriamycin (doxorubicin), dexamethasone	Multiple myeloma

↑ Bonadonna G, Zucali R, Monfardini S, De Lena M, Uslenghi C (1975). "Combination chemotherapy of Hodgkin's disease with adriamycin, bleomycin, vinblastine, and imidazole carboxamide versus MOPP". Cancer. 36 (1): 252–9. PMID 54209. Unknown parameter |month= ignored (help)
↑ Schwartz CL, Constine LS, Villaluna D; et al. (2009). "A risk-adapted, response-based approach using ABVE-PC for children and adolescents with intermediate- and high-risk Hodgkin lymphoma: the results of P9425". Blood. 114 (10): 2051–9. doi:10.1182/blood-2008-10-184143. PMID 19584400. Unknown parameter |month= ignored (help)
↑ Diehl V, Franklin J, Hasenclever D; et al. (1998). "BEACOPP, a new dose-escalated and accelerated regimen, is at least as effective as COPP/ABVD in patients with advanced-stage Hodgkin's lymphoma: interim report from a trial of the German Hodgkin's Lymphoma Study Group". J. Clin. Oncol. 16 (12): 3810–21. PMID 9850026. Unknown parameter |month= ignored (help)
↑ Wilson WH, Grossbard ML, Pittaluga S; et al. (2002). "Dose-adjusted EPOCH chemotherapy for untreated large B-cell lymphomas: a pharmacodynamic approach with high efficacy". Blood. 99 (8): 2685–93. PMID 11929754. Unknown parameter |month= ignored (help)
↑ Velasquez WS, Cabanillas F, Salvador P; et al. (1988). "Effective salvage therapy for lymphoma with cisplatin in combination with high-dose Ara-C and dexamethasone (DHAP)". Blood. 71 (1): 117–22. PMID 3334893. Unknown parameter |month= ignored (help)
↑ McLaughlin P, Hagemeister FB, Romaguera JE; et al. (1996). "Fludarabine, mitoxantrone, and dexamethasone: an effective new regimen for indolent lymphoma". J. Clin. Oncol. 14 (4): 1262–8. PMID 8648382. Unknown parameter |month= ignored (help)
↑ Thomas DA, Cortes J, O'Brien S; et al. (1999). "Hyper-CVAD program in Burkitt's-type adult acute lymphoblastic leukemia". J. Clin. Oncol. 17 (8): 2461–70. PMID 10561310. Unknown parameter |month= ignored (help)
↑ Moskowitz CH, Bertino JR, Glassman JR; et al. (1999). "Ifosfamide, carboplatin, and etoposide: a highly effective cytoreduction and peripheral-blood progenitor-cell mobilization regimen for transplant-eligible patients with non-Hodgkin's lymphoma". J. Clin. Oncol. 17 (12): 3776–85. PMID 10577849. Unknown parameter |month= ignored (help)
↑ Klimo P, Connors JM (1985). "MACOP-B chemotherapy for the treatment of diffuse large-cell lymphoma". Ann. Intern. Med. 102 (5): 596–602. PMID 2580468. Unknown parameter |month= ignored (help)
↑ Herrlinger U, Schabet M, Brugger W; et al. (2002). "German Cancer Society Neuro-Oncology Working Group NOA-03 multicenter trial of single-agent high-dose methotrexate for primary central nervous system lymphoma". Ann. Neurol. 51 (2): 247–52. PMID 11835382. Unknown parameter |month= ignored (help)
↑ DeAngelis LM, Seiferheld W, Schold SC, Fisher B, Schultz CJ (2002). "Combination chemotherapy and radiotherapy for primary central nervous system". J. Clin. Oncol. 20 (24): 4643–8. PMID 12488408. Text " lymphoma: Radiation Therapy Oncology Group Study 93-10 " ignored (help); Unknown parameter |month= ignored (help)
↑ Bartlett NL, Rosenberg SA, Hoppe RT, Hancock SL, Horning SJ (1995). "Brief chemotherapy, Stanford V, and adjuvant radiotherapy for bulky or advanced-stage Hodgkin's disease: a preliminary report". J. Clin. Oncol. 13 (5): 1080–8. PMID 7537796. Unknown parameter |month= ignored (help)

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[pmid54209-1] Bonadonna G, Zucali R, Monfardini S, De Lena M, Uslenghi C (1975). "Combination chemotherapy of Hodgkin's disease with adriamycin, bleomycin, vinblastine, and imidazole carboxamide versus MOPP". Cancer. 36 (1): 252–9. PMID 54209. Unknown parameter |month= ignored (help)

[pmid19584400-2] Schwartz CL, Constine LS, Villaluna D; et al. (2009). "A risk-adapted, response-based approach using ABVE-PC for children and adolescents with intermediate- and high-risk Hodgkin lymphoma: the results of P9425". Blood. 114 (10): 2051–9. doi:10.1182/blood-2008-10-184143. PMID 19584400. Unknown parameter |month= ignored (help)

[pmid9850026-3] Diehl V, Franklin J, Hasenclever D; et al. (1998). "BEACOPP, a new dose-escalated and accelerated regimen, is at least as effective as COPP/ABVD in patients with advanced-stage Hodgkin's lymphoma: interim report from a trial of the German Hodgkin's Lymphoma Study Group". J. Clin. Oncol. 16 (12): 3810–21. PMID 9850026. Unknown parameter |month= ignored (help)

[pmid11929754-4] Wilson WH, Grossbard ML, Pittaluga S; et al. (2002). "Dose-adjusted EPOCH chemotherapy for untreated large B-cell lymphomas: a pharmacodynamic approach with high efficacy". Blood. 99 (8): 2685–93. PMID 11929754. Unknown parameter |month= ignored (help)

[pmid3334893-5] Velasquez WS, Cabanillas F, Salvador P; et al. (1988). "Effective salvage therapy for lymphoma with cisplatin in combination with high-dose Ara-C and dexamethasone (DHAP)". Blood. 71 (1): 117–22. PMID 3334893. Unknown parameter |month= ignored (help)

[pmid8648382-6] McLaughlin P, Hagemeister FB, Romaguera JE; et al. (1996). "Fludarabine, mitoxantrone, and dexamethasone: an effective new regimen for indolent lymphoma". J. Clin. Oncol. 14 (4): 1262–8. PMID 8648382. Unknown parameter |month= ignored (help)

[pmid10561310-7] Thomas DA, Cortes J, O'Brien S; et al. (1999). "Hyper-CVAD program in Burkitt's-type adult acute lymphoblastic leukemia". J. Clin. Oncol. 17 (8): 2461–70. PMID 10561310. Unknown parameter |month= ignored (help)

[pmid10577849-8] Moskowitz CH, Bertino JR, Glassman JR; et al. (1999). "Ifosfamide, carboplatin, and etoposide: a highly effective cytoreduction and peripheral-blood progenitor-cell mobilization regimen for transplant-eligible patients with non-Hodgkin's lymphoma". J. Clin. Oncol. 17 (12): 3776–85. PMID 10577849. Unknown parameter |month= ignored (help)

[pmid2580468-9] Klimo P, Connors JM (1985). "MACOP-B chemotherapy for the treatment of diffuse large-cell lymphoma". Ann. Intern. Med. 102 (5): 596–602. PMID 2580468. Unknown parameter |month= ignored (help)

[pmid11835382-10] Herrlinger U, Schabet M, Brugger W; et al. (2002). "German Cancer Society Neuro-Oncology Working Group NOA-03 multicenter trial of single-agent high-dose methotrexate for primary central nervous system lymphoma". Ann. Neurol. 51 (2): 247–52. PMID 11835382. Unknown parameter |month= ignored (help)

[pmid12488408-11] DeAngelis LM, Seiferheld W, Schold SC, Fisher B, Schultz CJ (2002). "Combination chemotherapy and radiotherapy for primary central nervous system". J. Clin. Oncol. 20 (24): 4643–8. PMID 12488408. Text " lymphoma: Radiation Therapy Oncology Group Study 93-10 " ignored (help); Unknown parameter |month= ignored (help)

[pmid7537796-12] Bartlett NL, Rosenberg SA, Hoppe RT, Hancock SL, Horning SJ (1995). "Brief chemotherapy, Stanford V, and adjuvant radiotherapy for bulky or advanced-stage Hodgkin's disease: a preliminary report". J. Clin. Oncol. 13 (5): 1080–8. PMID 7537796. Unknown parameter |month= ignored (help)

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List of chemotherapy regimens

Overview

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