Autoimmune lymphoproliferative syndrome
| Autoimmune lymphoproliferative syndrome | |
| OMIM | 601859 603909 |
|---|---|
| DiseasesDB | 33425 Template:DiseasesDB2 |
Editor-In-Chief: David Teachey, MD [1]
Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [2] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.
Autoimmune lymphoproliferative syndrome is a form of lymphoproliferative disorder. It affects lymphocyte apoptosis.[1]
Presentation
Among the possible symptoms are splenomegaly and hepatomegaly.[2]
Classification
Types include:
- IA - Fas receptor (this form is the most common)[3]
- IB - Fas ligand
- IIA - Caspase 10
- IIB - Caspase 8
- III - unknown
- IV - Neuroblastoma RAS viral oncogene homolog
References
- ↑ Fleisher TA (2008). "The autoimmune lymphoproliferative syndrome: an experiment of nature involving lymphocyte apoptosis". Immunol. Res. 40 (1): 87–92. doi:10.1007/s12026-007-8001-1. PMID 18193364.
- ↑ "Autoimmune Lymphoproliferative Syndrome (ALPS), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH)". Retrieved 2008-03-01.
- ↑ "Autoimmune Lymphoproliferative Syndrome". Retrieved 2008-03-01.