Atrial septal defect
| Atrial septal defect | ||
 | ||
|---|---|---|
| Heart of human embryo of about thirty-five days | ||
| ICD-10 | Q21.1 | |
| ICD-9 | 745.5-745.6 | |
| OMIM | 108800 | |
| DiseasesDB | 1089 | |
| eMedicine | med/3519 | |
| MeSH | C14.240.400.560.375 | |
| Cardiology Network |
 Discuss Atrial septal defect further in the WikiDoc Cardiology Network |
| Adult Congenital |
|---|
| Biomarkers |
| Cardiac Rehabilitation |
| Congestive Heart Failure |
| CT Angiography |
| Echocardiography |
| Electrophysiology |
| Cardiology General |
| Genetics |
| Health Economics |
| Hypertension |
| Interventional Cardiology |
| MRI |
| Nuclear Cardiology |
| Peripheral Arterial Disease |
| Prevention |
| Public Policy |
| Pulmonary Embolism |
| Stable Angina |
| Valvular Heart Disease |
| Vascular Medicine |
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Overview
Embryology
Pathophysiology
Epidemiology
Genetic
Types of atrial septal defects
Ostium primum atrial septal defect | Ostum secundum atrial septal defect | Patent foramen ovale | Sinus venosus atrial septal defect | Common or single atrium
Diagnosis
Physical examination | Auscultation of the heart | Chest X-ray | Electrocardiography | Echocardiography | Trans-cranial doppler ultrasound | MRI
Treatment
Evaluation prior to correction | Surgical ASD closure | Percutaneous ASD closure
Associated conditions
Due to the communication between the atria that occurs in ASD's, disease entities or complications from the condition, are possible.
Decompression sickness
ASDs, and particularly PFOs, are a predisposing risk factor for decompression sickness in divers because a proportion of venous blood carrying inert gases, such as helium or nitrogen does not pass through the lungs.[1][2] The only way to release the excess inert gases from the body is to pass the blood carrying the inert gases through the lungs to be exhaled. If some of the inert gas-laden blood passes through the PFO, it avoids the lungs and the inert gas is more likely to form large bubbles in the arterial blood stream causing decompression sickness.
Paradoxical emboli
Venous thrombi (clots in the veins) are quite common. Embolization (dislodgement of thrombi) normally go to the lung and cause pulmonary emboli. In an individual with ASD, these emboli can potentially enter the arterial system. This can cause any phenomenon that is attributed to acute loss of blood to a portion of the body, including cerebrovascular accident (stroke), infarction of the spleen or intestines, or even a distal extremity (i.e.: finger or toe).
This is known as a paradoxical embolus because the clot material paradoxically enters the arterial system instead of going to the lungs.
Migraine
Some recent research has suggested that a proportion of cases of migraine may be caused by patent foramen ovale. While the exact mechanism remains unclear, closure of a PFO can reduce symptoms in certain cases.[3][4] This remains controversial. 20% of the general population have a PFO, which for the most part, is asymptomatic. 20% of the female population have migraines. And, the placebo effect in migraine typically averages around 40%. The high frequency of these facts makes statistically significant relationships between PFO and migraine difficult (i.e., the relationship may just be chance or coincidence).
See also
- Atrioventricular septal defect
- Cardiac output
- Congenital heart disease
- Heart sounds
- Pulmonary hypertension
- Vascular resistance
- Ventricular septal defect
References
- ↑ Lier H, Schroeder S, Hering R (2004). "[Patent foramen ovale: an underrated risk for divers?]". Dtsch Med Wochenschr. 129 (1–2): 27–30. PMID 14703578.
- ↑ Saary M, Gray G (2001). "A review of the relationship between patent foramen ovale and type II decompression sickness". Aviat Space Environ Med. 72 (12): 1113–20. PMID 11763113.
- ↑ Adams H (2004). "Patent foramen ovale: paradoxical embolism and paradoxical data". Mayo Clin Proc. 79 (1): 15–20. PMID 14708944.
- ↑ Azarbal B, Tobis J, Suh W, Chan V, Dao C, Gaster R (2005). "Association of interatrial shunts and migraine headaches: impact of transcatheter closure". J Am Coll Cardiol. 45 (4): 489–92. PMID 15708691.
External links
- Atrial Septal Defect information from Seattle Children's Hospital Heart Center
- Pediatric Heart Surgery
- The Congenital Heart Surgery Video Project
- Pediatric Cardiac Surgery: Atrial Septal Defect Repair