Ventricular septal defect natural history, complications and prognosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Associate Editor-In-Chief: Keri Shafer, M.D. [2], Atif Mohammad, M.D., Priyamvada Singh, MBBS
__NOTOC_
Natural history of unoperated ventricular septal defect-
Restrictive ventricular septal defect -
- Small shunt (< 1.5/1.0, Qρ/Qѕ pressure gradient between left and right ventricle)
- No significant hemodynamic compromise
Moderately restrictive ventricular septal defect
- Moderate shunt (Qρ/Qѕ=1.5-2.5/1.0)
- Hemodynamic burden on left atrium and ventricle
- Increase in pulmonary vascular resistance
- Atrial and ventricular arrhythmia can occur
Large or Non restrictive venticular defect
- High left and right ventricular volume overload
- High pulmonary vascular resistance
- Eisenmenger syndrome
Other developments that can occur are -
- Spontaneous closure
- Endocarditis
- Aortic regurgitation
- Subaortic or subpulmonary stenosis
References
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