Schwannoma
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Schwannoma | |
ICD-O: | 9560/0 |
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DiseasesDB | 33713 |
MeSH | D009442 |
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Synonyms and keywords: Acoustic neuroma, acoustic neurinoma, or acoustic neurilemoma
Overview
A schwannoma is a kind of tumor originating from the Schwann cells. The insulating myelin sheath which covers peripheral nerves is produced by the Schwann cells. Hence, one kind of tumor originating from the Schwann cells is called a schwannoma.
Schwannomas are very homogenous tumors consisting only of Schwann cells. The tumor cells always stay on the outside of the nerve, but the tumor itself may either push the nerve aside and/or up against a bony structure (thereby possibly causing damage). Schwannomas are relatively slow growing. For reasons not yet understood, schwannomas are mostly benign and less than 1% become malignant (degenerate into cancer).
Schwannomas can arise from a genetic disorder called schwannomatosis.
A schwannoma (also known as an "acoustic neuroma,"[1] "neurilemmoma,"[2]:621 "neurinoma,"[1] "neurolemmoma,"[1] and "Schwann cell tumor"[1]) is a benign nerve sheath tumor composed of Schwann cells, which normally produce the insulating myelin sheath covering peripheral nerves.
Schwannomas are very homogeneous tumors, consisting only of Schwann cells. The tumor cells always stay on the outside of the nerve, but the tumor itself may either push the nerve aside and/or up against a bony structure (thereby possibly causing damage). Schwannomas are relatively slow growing. For reasons not yet understood, schwannomas are mostly benign and less than 1% become malignant, degenerating into a form of cancer known as neurofibrosarcoma.
Schwannomas can arise from a genetic disorder called neurofibromatosis. They are universally S-100 positive.
Schwannomas can be removed surgically, but can then recur.
Additional images
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Subcutaneous schwannoma
References
See also
- Neurofibroma
- Vestibular schwannoma (Acoustic neuroma)
Template:Nervous tissue tumors
cs:Neurinom de:Schwannom fa:شوانوما it:Schwannoma