Patent foramen ovale and migraine
|
Patent Foramen Ovale Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Patent foramen ovale and migraine On the Web |
|
American Roentgen Ray Society Images of Patent foramen ovale and migraine |
|
Risk calculators and risk factors for Patent foramen ovale and migraine |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editors-In-Chief: Priyamvada Singh, M.B.B.S. [2]; Assistant Editor-In-Chief: Kristin Feeney, B.S. [3]
Overview
Migraine headaches, particular those with an aura, have been associated with a patent foramen ovale.
Trial supportive data for patent foramen ovale and migraine
- A recent metanalysis including 18 studies and comprising 2636 patients, found a low-grade positive association between migraines in patients with patent foramen ovale (PFO) [1]. However, the results of this study should be interpreted with cautions, as the individual studies included for the metanalysis were quite heterogeneous. There was some positive association seen in patients of migraine with aura {odds ratio of 3.21(95% CI 2.38–4.70)} but no such relation was seen for patients of migraine without aura
- Another case control study done to evaluate the association between migraine headaches and patent foramen ovale (PFO) found no significant association between the two [2]. The prevalence of patent foramen ovale (PFO) was similar in case and control (26.4% versus 25.7%;P=0.90). Unlike the metanalysis discussed above, no difference in patent foramen ovale (PFO) prevalence was found in those with migraine with aura and those without (P=0.93).
References
- ↑ Schwedt TJ, Demaerschalk BM, Dodick DW (2008). "Patent foramen ovale and migraine: a quantitative systematic review". Cephalalgia. 28 (5): 531–40. doi:10.1111/j.1468-2982.2008.01554.x. PMID 18355348.
- ↑ Garg P, Servoss SJ, Wu JC, Bajwa ZH, Selim MH, Dineen A; et al. (2010). "Lack of association between migraine headache and patent foramen ovale: results of a case-control study". Circulation. 121 (12): 1406–12. doi:10.1161/CIRCULATIONAHA.109.895110. PMID 20231534.