Asbestosis other diagnostic studies
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Kim-Son H. Nguyen, M.D., M.P.A., Beth Israel Deaconess Medical Center, Harvard Medical School, Boston MA, Cafer Zorkun, M.D., Ph.D. [2]
Overview
Pulmonary function test
Pulmonary function tests are not diagnostic, but provide a measure of pulmonary function.
- Most patients demonstrate a restrictive pattern with reduced lung volumes, particularly with reduced vital capacity and reduced total lung capacity, and reduced pulmonary compliance.
- Reductions in diffusing capacity are common.
- Some patients may show obstructive patterns, but rarely without associated tobacco exposure. Airflow limitation in these patients may be due to inflammation of large airways, resulting from asbestos deposition along the respiratory bronchioles.
- Exudative pleural effusions may develop. These usually occur within 15 years of exposure. These may resolve spontaneously, and may leave visceral pleural thickening and blunting of the costophrenic angle, and can even impair pulmonary function in some cases.
- Hyaline plaques may form on the parietal pleura, and may calcify. These may develop after less exposure than required for asbestosis, and are therefore more common, occurring in up to 50% of patients with asbestos exposure.