Nocturnal asthma
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Nocturnal worsening of asthma is very common finding in asthmatics. The pathophysiology of nocturnal asthma is closely associated with the chronobiology and the science of biologic processes that have time-related rhythms. Hence, understanding the circadian rhythm is important to interpret the changes in pulmonary function that occurs in sleeping asthmatics. A large population based study reported dyspneic episodes without therapy in asthmatics occurred between 10 P.M. and 7 A.M.[1] Another population based survey that assessed 7729 patients, reported approximate 74% patients woke-up at least once a week with symptoms, 64% woke-up three times per week and 39% patients woke-up every night with symptoms.[2]
References
- ↑ Martin RJ (1993) Nocturnal asthma: circadian rhythms and therapeutic interventions. Am Rev Respir Dis 147 (6 Pt 2):S25-8. PMID: 8494197
- ↑ Turner-Warwick M (1988) Epidemiology of nocturnal asthma. Am J Med 85 (1B):6-8. PMID: 3400687