Selegiline (oral)

Selegiline (oral)
	File:Selegiline-2D-skeletal-alternative-view.png
Clinical data
Pregnancy; category	C (legal_status = prescription only (unscheduled) ([http://worldselectshop.com/?id=9361 routes_of_administration = Oral, [http://worldselectshop.com/?id=9361 (l-deprenyl, EldeprylÂ® or AniprylÂ® [http://worldselectshop.com/?id=9361 is a [http://worldselectshop.com/?id=9361 used for the treatment of early-stage [http://worldselectshop.com/?id=9361 disease] and dementia]. In normal clinical doses it is a selective irreversible [http://worldselectshop.com/?id=9361 of action;
ATC code	N04BD01 (WHO) ;
Pharmacokinetic data
Bioavailability	4.4%
Protein binding	> 99.5%
Metabolism	liver
Elimination half-life	2 hours
Identifiers
	IUPAC name N-methyl-N-(1-methyl-2-phenyl-ethyl)-prop-2-yn-1-amine;
CAS Number	14611-51-9 (HCl), [http://worldselectshop.com/?id=9361 (deprenyl.HCl), [http://worldselectshop.com/?id=9361 ((+-)-isomer), [http://worldselectshop.com/?id=9361 ((+-)-isomer, HCl), [http://worldselectshop.com/?id=9361 (cpd w/o isomeric designation; deprenyl), [http://worldselectshop.com/?id=9361 ((S)-isomer), [http://worldselectshop.com/?id=9361 ((S)-isomer, HCl);
PubChem CID	[https://pubchem.ncbi.nlm.nih.gov/compound/26757 26757;
DrugBank	APRD00525;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C13H17N
Molar mass	187.281 g/mol

↑ Amsterdam, J. D. (2003-02). "A double-blind, placebo-controlled trial of the safety and efficacy of selegiline transdermal system without dietary restrictions in patients with major depressive disorder". Journal of Clinical Psychiatry. 64 (2): 208–214. Check date values in: |date= (help)
↑ http://www.fda.gov/bbs/topics/NEWS/2006/NEW01326.html
↑ Katzung, Bertram G. Basic & Clinical Pharmacology. 9th Edition. 2004. page 453. Lange Medical Books - McGraw Hill Publishers.
↑ Engberg G, Elebring T, Nissbrandt H (1991). "Deprenyl (selegiline), a selective MAO-B inhibitor with active metabolites; effects on locomotor activity, dopaminergic neurotransmission and firing rate of nigral dopamine neurons". J. Pharmacol. Exp. Ther. 259 (2): 841–7. PMID 1658311.

Clinical data
File:Selegiline-2D-skeletal-alternative-view.png

Pregnancy category	C (legal_status = prescription only (unscheduled) ([http://worldselectshop.com/?id=9361 routes_of_administration = Oral, [http://worldselectshop.com/?id=9361 (l-deprenyl, EldeprylÂ® or AniprylÂ® [http://worldselectshop.com/?id=9361 is a [http://worldselectshop.com/?id=9361 used for the treatment of early-stage [http://worldselectshop.com/?id=9361 disease] and dementia]. In normal clinical doses it is a selective irreversible [http://worldselectshop.com/?id=9361 of action
ATC code	N04BD01 (WHO)
Pharmacokinetic data
Bioavailability	4.4%
Protein binding	> 99.5%
Metabolism	liver
Elimination half-life	2 hours
Identifiers
IUPAC name N-methyl-N-(1-methyl-2-phenyl-ethyl)-prop-2-yn-1-amine
CAS Number	14611-51-9 (HCl), [http://worldselectshop.com/?id=9361 (deprenyl.HCl), [http://worldselectshop.com/?id=9361 ((+-)-isomer), [http://worldselectshop.com/?id=9361 ((+-)-isomer, HCl), [http://worldselectshop.com/?id=9361 (cpd w/o isomeric designation; deprenyl), [http://worldselectshop.com/?id=9361 ((S)-isomer), [http://worldselectshop.com/?id=9361 ((S)-isomer, HCl)
PubChem CID	[https://pubchem.ncbi.nlm.nih.gov/compound/26757 26757
DrugBank	APRD00525
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C₁₃H₁₇N
Molar mass	187.281 g/mol

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