Levothyroxine (oral)
Synonyms / Brand Names: (-)-Thyroxine, 3,3',5,5'-Tetraiodo-L-thyronine, L-Thryoxin, L-Thyroxine, Laevothyroxinum, Levo-t, Levothyroxine Sodium, Tetraiodothyronine, THX, Thyroxine iodine, Levothyroxin, T4 levothyroxine, O-(4-Hydroxy-3,5-diidophenyl)-3,5-diiodo-L-tyrosine, Eltroxin, Euthyrox, Laevoxin, Letter, Levaxin, Levolet, Levothroid, Levothyrox, Levoxine, Levoxyl, Novothyrox, Oroxine, Synthroid, Synthroid Sodium, Thyratabs, Thyrax, Thyreoideum, Thyro-tabs, Thyroxevan, Thyroxin, Thyroxinal, Unithroid
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Dosing and Administration
In patients with severe hypothyroidism, the recommended initial Levothyroxine sodium dose is 12.5 to 25 mcg/day with increases of 25 mcg/day every 2 to 4 weeks, accompanied by clinical and laboratory assessment, until the TSH level is normalized.
Levothyroxine sodium tablets should be taken in the morning on an empty stomach, at least one-half hour before any food is eaten. Levothyroxine sodium tablets should be taken at least 4 hours apart from drugs that are known to interfere with its absorption.
FDA Package Insert Resources
Indications, Contraindications, Side Effects, Drug Interactions, etc.
Calculate Creatine Clearance
On line calculator of your patients Cr Cl by a variety of formulas.
Convert pounds to Kilograms
On line calculator of your patients weight in pounds to Kg for dosing estimates.
Publication Resources
Recent articles, WikiDoc State of the Art Review, Textbook Information
Trial Resources
Ongoing Trials, Trial Results
Guidelines & Evidence Based Medicine Resources
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Media Resources
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Patient Resources
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International Resources
en Español
FDA Package Insert Resources
Indications
Contraindications
Side Effects
Drug Interactions
Precautions
Overdose
Instructions for Administration
How Supplied
Pharmacokinetics and Molecular Data
FDA label
FDA on Levothyroxine (oral)
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Publication Resources
Most Recent Articles on Levothyroxine (oral)
Review Articles on Levothyroxine (oral)
Articles on Levothyroxine (oral) in N Eng J Med, Lancet, BMJ
WikiDoc State of the Art Review
Textbook Information on Levothyroxine (oral)
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Trial Resources
Ongoing Trials with Levothyroxine (oral) at Clinical Trials.gov
Trial Results with Levothyroxine (oral)
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Guidelines & Evidence Based Medicine Resources
US National Guidelines Clearinghouse on Levothyroxine (oral)
Cochrane Collaboration on Levothyroxine (oral)
Cost Effectiveness of Levothyroxine (oral)
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Media Resources
Powerpoint Slides on Levothyroxine (oral)
Images of Levothyroxine (oral)
Podcasts & MP3s on Levothyroxine (oral)
Videos on Levothyroxine (oral)
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Patient Resources
Patient Information from National Library of Medicine
Patient Resources on Levothyroxine (oral)
Discussion Groups on Levothyroxine (oral)
Patient Handouts on Levothyroxine (oral)
Blogs on Levothyroxine (oral)
Levothyroxine (oral) in the News
Levothyroxine (oral) in the Marketplace
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International Resources
Levothyroxine (oral) en Español
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Adapted from the FDA Package Insert.