Rofecoxib
Synonyms / Brand Names:MK 966, MK 996, rofecoxib, Vioxx
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Dosing and Administration
Osteoarthritis:
The recommended starting dose of VIOXX is 12.5 mg once daily. Some patients may
receive additional benefit by increasing the dose to 25 mg once daily. The maximum
recommended daily dose is 25 mg.
Primary Dysmenorrhea/ acute pain management:
The recommended initial dose of VIOXX is 50 mg once daily. Subsequent doses should be 50 mg once daily as needed. Use of VIOXX for more than 5 days in management of pain has not been studied.
For more information on dosing please refer to Instructions for administration
FDA Package Insert Resources
Indications, Contraindications, Side Effects, Drug Interactions, etc.
Calculate Creatine Clearance
On line calculator of your patients Cr Cl by a variety of formulas.
Convert pounds to Kilograms
On line calculator of your patients weight in pounds to Kg for dosing estimates.
Publication Resources
Recent articles, WikiDoc State of the Art Review, Textbook Information
Trial Resources
Ongoing Trials, Trial Results
Guidelines & Evidence Based Medicine Resources
US National Guidelines, Cochrane Collaboration, etc.
Media Resources
Slides, Video, Images, MP3, Podcasts, etc.
Patient Resources
Discussion Groups, Handouts, Blogs, News, etc.
International Resources
en Español
FDA Package Insert Resources
Indications
Contraindications
Side Effects
Drug Interactions
Precautions
Overdose
Instructions for Administration
How Supplied
Pharmacokinetics and Molecular Data
FDA label
FDA on Rofecoxib
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Publication Resources
Most Recent Articles on Rofecoxib
Review Articles on Rofecoxib
Articles on Rofecoxib in N Eng J Med, Lancet, BMJ
WikiDoc State of the Art Review
Textbook Information on Rofecoxib
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Trial Resources
Ongoing Trials with Rofecoxib at Clinical Trials.gov
Trial Results with Rofecoxib
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Guidelines & Evidence Based Medicine Resources
US National Guidelines Clearinghouse on Rofecoxib
Cochrane Collaboration on Rofecoxib
Cost Effectiveness of Rofecoxib
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Media Resources
Powerpoint Slides on Rofecoxib
Images of Rofecoxib
Podcasts & MP3s on Rofecoxib
Videos on Rofecoxib
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Patient Resources
Patient Information from National Library of Medicine
Patient Resources on Rofecoxib
Discussion Groups on Rofecoxib
Patient Handouts on Rofecoxib
Blogs on Rofecoxib
Rofecoxib in the News
Rofecoxib in the Marketplace
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International Resources
Rofecoxib en Español
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Adapted from the FDA Package Insert.