Buformin

Buformin
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Clinical data
Routes of; administration	Oral
ATC code	A10BA03 (WHO) ;
Legal status
Legal status	Withdrawn in most countries;
Pharmacokinetic data
Excretion	Renal
Identifiers
	IUPAC name 2-butyl-1-(diaminomethylidene)guanidine;
CAS Number	692-13-7;
PubChem CID	2468;
E number	{{#property:P628}}
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Chemical and physical data
Formula	C6H15N5
Molar mass	157.217 g/mol

Buformin is an anti-diabetic drug of the biguanide class, chemically related to metformin and phenformin. It was withdrawn from the market in most countries due to a high risk of causing lactic acidosis.^[1]^[2]

References

↑ Verdonck L, Sangster B, van Heijst A, de Groot G, Maes R (1981). "Buformin concentrations in a case of fatal lactic acidosis". Diabetologia. 20 (1): 45–6. PMID 7202882.
↑ Deppermann D, Heidland A, Ritz E, Hörl W (1978). "[Lactic acidosis--a possible complication in buformin-treated diabetics (author's transl)]". Klin Wochenschr. 56 (17): 843–53. PMID 713413.

Clinical data
Error creating thumbnail: File missing
Routes of administration	Oral
ATC code	A10BA03 (WHO)
Legal status
Legal status	Withdrawn in most countries
Pharmacokinetic data
Excretion	Renal
Identifiers
IUPAC name 2-butyl-1-(diaminomethylidene)guanidine
CAS Number	692-13-7
PubChem CID	2468
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C₆H₁₅N₅
Molar mass	157.217 g/mol