Brinzolamide

Brinzolamide
	File:Brinzolamide.svg
Clinical data
[[Regulation of therapeutic goods \|Template:Engvar data]]	EU EMA: by INN; US FDA: Brinzolamide;
Pregnancy; category	US: C (Risk not ruled out) ; ;
Routes of; administration	Ophthalmic
ATC code	S01EC04 (WHO) ;
Legal status
Legal status	US: ℞-only ;
Pharmacokinetic data
Protein binding	~60%
Elimination half-life	111 days
Identifiers
	IUPAC name (5R)-5-ethylamino-3-(3-methoxypropyl)-; 2,2-dioxo-2λ6,9-dithia-; 3-azabicyclo[4.3.0]nona-7,10-diene-; 8-sulfonamide;
CAS Number	138890-62-7;
PubChem CID	68844;
DrugBank	APRD00475;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C12H21N3O5S3
Molar mass	383.51 g/mol

Brinzolamide is a carbonic anhydrase inhibitor.

References

Ermis S, Ozturk F, Inan U (2005). "Comparing the effects of travoprost and brinzolamide on intraocular pressure after phacoemulsification". Eye. 19 (3): 303–7. PMID 15258611.
Iester M, Altieri M, Michelson G, Vittone P, Traverso C, Calabria G. "Retinal peripapillary blood flow before and after topical brinzolamide". Ophthalmologica. 218 (6): 390–6. PMID 15564757.
Kaup M, Plange N, Niegel M, Remky A, Arend O (2004). "Effects of brinzolamide on ocular haemodynamics in healthy volunteers". Br J Ophthalmol. 88 (2): 257–62. PMID 14736787.

Clinical data
File:Brinzolamide.svg
[[Regulation of therapeutic goods \|Template:Engvar data]]	EU EMA: by INN US FDA: Brinzolamide
Pregnancy category	US: C (Risk not ruled out)
Routes of administration	Ophthalmic
ATC code	S01EC04 (WHO)
Legal status
Legal status	US: ℞-only
Pharmacokinetic data
Protein binding	~60%
Elimination half-life	111 days
Identifiers
IUPAC name (5R)-5-ethylamino-3-(3-methoxypropyl)- 2,2-dioxo-2λ⁶,9-dithia- 3-azabicyclo[4.3.0]nona-7,10-diene- 8-sulfonamide
CAS Number	138890-62-7
PubChem CID	68844
DrugBank	APRD00475
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C₁₂H₂₁N₃O₅S₃
Molar mass	383.51 g/mol