Cloxacillin

Cloxacillin

File:Cloxacillin.svg
Clinical data
Pregnancy category	US: B (No risk in non-human studies)
Routes of administration	Oral, IM
ATC code	J01CF02 (WHO)
Pharmacokinetic data
Bioavailability	37 to 90%
Protein binding	95%
Elimination half-life	30 minutes to 1 hour
Excretion	Renal and biliary
Identifiers
IUPAC name (2S,5R,6R)-6-{[3-(2-chlorophenyl)-5-methyl- oxazole-4-carbonyl]amino}-3,3-dimethyl-7-oxo- 4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
CAS Number	61-72-3
PubChem CID	6098
DrugBank	APRD00882
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C19H18ClN3O5S
Molar mass	435.882 g/mol

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Cloxacillin is a semisynthetic antibiotic in the same class as penicillin. It is sold under a number of trade names, including Cloxapen and Orbenin. Cloxacillin is used against staphylococci that produce beta-lactamase.

This drug has a weaker antibacterial activity than benzylpencillin, and is devoid of serious toxicity except for allergic reactions.

See also

• Dicloxacillin
• Flucloxacillin
• Nafcillin
• Oxacillin