Synulox

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Synulox® is a widely known brand name of Veterinary Antibiotic, used for treating infections mostly in the lungs, and nasal tract; and as a broad-spectrum antibiotic. The drug is a compound of amoxicillin and Clavulanic Acid. See also Co-amoxiclav.

NB - All quantities shown below are combined - i.e. 500mg = 400mg Amoxicillin and 100mg Clavulanic Acid.

Formulations

• 500mg Bolus: Large film-coated tablets. For the treatment of enteritis and navel ill in calves.

• Intramammary Suspension: Synulox + Prednisolone for intra-mammary infusion. For the treatment of mastitis in lactating cows.

• Palatable Drops: A powder for reconstitution for oral administration. A broad-spectrum antibiotic for dogs and cats.

• Palatable Tablets: Available as 50mg, 250mg and 500mg for oral administration. A broad-spectrum antibiotic for dogs and cats.

• Synulox Ready-To-Use Injection: Multi-purpose injectable formulation, recommended for respiratory tract infections, soft tissue infections, metritis and mastitis in cattle; respiratory tract infections, colibacillosis and mastitis, metritis & agalactia in pigs; respiratory tract infections, urinary tract infections, skin and soft tissue infections in dogs and cats.

Bacterial Resistance

Bacterial antibiotic resistance is a growing problem in veterinary medicine. Clavulanic acid inactivates beta-lactamases which are a common resistance strategy in gram positive bacteria. Synulox is reported to be effective against clinical Klebsiella infections, but is not efficacious against Pseudomonas infections.

References

• NOAH Compendium of Data Sheets for Animal Medicines 2007