Trimetrexate

Trimetrexate
	File:Trimetrexate.svg
Clinical data
ATC code	P01AX07 (WHO) ;
Pharmacokinetic data
Bioavailability	VD: 20-30 Liters
Metabolism	Oxidative O-demethylation, followed by conjugation with glucuronide or sulfate
Elimination half-life	11 to 12 hours
Identifiers
	IUPAC name 5-methyl-6-[(3,4,5-trimethoxyphenyl) aminomethyl] quinazoline-2,4-diamine;
CAS Number	52128-35-5;
PubChem CID	5583;
DrugBank	APRD00268;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C19H23N5O3
Molar mass	369.418 g/mol

Trimetrexate is a quinazoline derivative and dihydrofolate reductase inhibitor used with leucovorin in treating pneumocystis pneumonia.

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Clinical data
File:Trimetrexate.svg
ATC code	P01AX07 (WHO)
Pharmacokinetic data
Bioavailability	VD: 20-30 Liters
Metabolism	Oxidative O-demethylation, followed by conjugation with glucuronide or sulfate
Elimination half-life	11 to 12 hours
Identifiers
IUPAC name 5-methyl-6-[(3,4,5-trimethoxyphenyl) aminomethyl] quinazoline-2,4-diamine
CAS Number	52128-35-5
PubChem CID	5583
DrugBank	APRD00268
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C₁₉H₂₃N₅O₃
Molar mass	369.418 g/mol