Methylergonovine (injection)

Methylergonovine (injection)

File:Ergonovine.gif
Clinical data
Synonyms	Ergonovine, Lysergic acid beta-propanolamide
Routes of administration	Oral
Legal status
Legal status	US: List I precursor
Pharmacokinetic data
Metabolism	hepatic
Excretion	renal
Identifiers
CAS Number	478-94-4
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C19H23N3O2
Molar mass	325.41 g/mol

Ergonovine, also known as ergometrine or d-lysergic acid beta-propanolamide, is an ergoline (and lysergamide) derivative, and one of the primary ergot and morning glory alkaloids . It is chemically similar to LSD, ergine, and lysergic acid.

Medical use

It has a medical use in obstetrics to facilitate delivery of the placenta and to prevent bleeding after childbirth by causing smooth muscle tissue in the blood vessel walls to narrow, thereby reducing blood flow. It is usually combined with oxytocin (syntocinon) as syntometrine.

Recreational use

According to TIHKAL by Alexander Shulgin, ergonovine has LSD-like action at levels of 2-10 milligrams. Clinical dosages are about ten times lower.

Legal status

Ergometrine is listed as Table I precursors under the United Nations Convention Against Illicit Traffic in Narcotic Drugs and Psychotropic Substances, due to its structural similarity to LSD.