Polycarbophil

Polycarbophil

File:Polycarbophil.jpg
Clinical data
Pregnancy category	US: C (Risk not ruled out)
Routes of administration	Oral,
ATC code	A06AC08 (WHO)
Legal status
Legal status	US: OTC
Pharmacokinetic data
Bioavailability	%
Identifiers
CAS Number	9003-97-8
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	Ca4N0
Molar mass	/mol

Polycarbophil, also Calcium Polycarbophil is the International Nonproprietary Name of a synthetic polymer the calcium salt of polyacrylic acid cross-linked with divynyl glycol.

Clinical Uses

Main article: laxatives

It is used as stool stabilizer to treat constipation, diarrhea and abdominal discomfort.

Calcium polycarbophil has been marketed as over-the-counter agents used for treating functional bowel disorder and as a bulk-producing agent: A06

Presentations

Chewable tablet containing Calcium Polycarbophil 625mg

References

• Boehringer-Ingelheim

• Takaharu Saito, Fujie Mizutani, Yuji Iwanaga, Kouji Morikawa and Hideo Kato. 2002. Laxative and Anti-diarrheal Activity of Polycarbophil in Mice and Rats. . Jpn.J. Pharmacol. 89, p. 133

• Akira Torii, and Gotaro Toda. 2004. Management of Irritable Bowel Syndrome. Internal Medicine 43, p. 353