Coronary flow reserve
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Sensitivity and Specificity
When compared to reversible defects on myocardial perfusion imaging, a coronary flow reserve < 2.0 has:
- Sensitivity: 86% to 92%
- Specificity: 89% to 100%
- Predictive accuracy: 89% to 96%
- Positive predictive value: 84% to 100%
- Negative predictive value: 77% to 95%
Complications
The risk of intracoronary Doppler velocity wire measurements are as follows (n=906):
- Bradycardia: 1.7%
- Coronary spasm: 2%
- Ventricular fibrillation: 0.2%
References