Cardiology overview heart failure

Cardiology Overview
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Pharmacotherapy

Lasix

• Higher lasix doses are associated with higher mortality, likely as a surrogate of disease severity rather than part of a causal pathway.

Metformin

• Metformin use in diabetics with CHF is associated with lower mortality

Invasive Monitoring

• Based upon the results of the ESCAPE trial, there is no benefit in clinical outcomes with the use of a pulmonary artery line in patients with decompensated CHF.

Obstructive Sleep Apnea in the Patient with CHF

• Central sleep apnea in the patient with CHF is due to the compensatory respiratory alkalosis that is present in the patient with CHF and tachypnea