Adenocarcinoma

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List of terms related to Adenocarcinoma

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Overview

Adenocarcinoma is a form of carcinoma that originates in glandular tissue. To be classified as adenocarcinoma, the cells do not necessarily need to be part of a gland, as long as they have secretory properties. This form of carcinoma can occur in some higher mammals, including humans.

The term adenocarcinoma is derived from 'adeno' meaning 'pertaining to a gland' and 'carcinoma', which describes a cancer that has developed in the epithelial cells.

It can first present as an adenoma (a glandular tumor that is benign).

Topography

Examples of tissues where adenocarcinomas may arise:

• Breast cancer
• Colon cancer
• Lung cancer
• Prostate cancer
• Stomach cancer
• Pancreatic cancer (99% of pancreatic cancers are ductal adenocarcinomas [3])
• Cervical cancer
• Vaginal cancer

Pathological Findings

• 

  This cancer presented in a 40-year-old woman complaining of abdominal pain. Endoscopically it was a "very suspicious" ulcer. Biopsy showed diffusely infiltrating signet ring cell adenocarcinoma. These are gross photos of the subtotal gastrectomy specimen. The photo above is a seen face view of the ulcer. The pyloric margin is to the left. The ulcer is on the lesser curvature.

• 

  This is a longitudinal section cut in the plane of the lesser curvature. The pylorus is to the left. Note several prominent nodes of the lesser omentum; these contained metastatic cancer.

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