Aortoiliac disease

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Editors-In-Chief: Alexandra Almonacid M.D. [1]and Jeffrey J. Popma M.D. [2]

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Classification

Morphological Stratification of Iliac Lesions-ACC/AHA Guidelines

  • TASC Type A iliac lesions
    • Single stenosis less than 3 cm of the CIA or EIA (unilateral/bilateral)
  • TASC Type B iliac lesions
    • Single stenosis 3 to 10 cm in length, not extending into the CFA
    • Total of 2 stenosis less than 5 cm long in the CIA and/or EIA and not extending into the CFA
    • Unilateral CIA occlusion
  • TASC Type C iliac lesions
    • Bilateral 5 to 10 cm long stenosis of the CIA and/or EIA, note extending into the CFA
    • Unilateral EIA occlusion not extending into the CFA
    • Unilateral EIA stenosis extending into the CFA
    • Bilateral CIA occlusion
  • TASC Type D iliac lesions
    • Diffuse, multiple unilateral stenosis involving the CIA, EIA and CFA (usually more than 10 cm long)
    • Unilateral occlusion involving both the CIA and EIA
    • Bilateral EIA occlusions
    • Diffuse disease involving the aorta and both iliac arteries
    • Iliac stenosis in a patient with an abdominal aortic anuerysm or other lesion requiring aortic or iliac surgery

Diagnosis

  • MR angiography
    • Gadofosveset-enhanced MR angiography showed significant improvement (P < .001) compared with unenhanced MR angiography for diagnosis of clinically significant aortoiliac occlusive disease ( 50% stenosis) .
    • The improvement in diagnostic efficacy compared with unenhanced MR angiography was clearly demonstrated. There was an improvement in overall accuracy, sensitivity, and specificity.
  • CT Angiography
    • CT angiographic examination is less invasive and less expensive than conventional angiography
    • Improves resolution with decreased contrast load and acquisition time without increasing radiation exposure

Indications for Revascularization

  • Relief of symptomatic lower extremity ischemia, including claudication, rest pain, ulceration or gangrene, or embolization causing blue toe syndrome
  • Restoration y/o preservation of inflow to the lower extremity in the setting of pre-existing or anticipated distal bypass
  • Procurement of access to more proximal vascular beds for anticipated invasive procedures. Occasionally revascularization is indicated to rescue flow-limiting dissection complicating access for other invasive procedures

Technical Issues

  • Endovascular Access
    • Ipsilateral femoral artery
    • Contralateral femoral artery
    • Brachial artery: In patients with flush occlusions at the aortic bifurcation
  • Multiple access sites may be required for successful treatment:
    • Bilateral femoral
    • Femoral/brachial

Treatment Options

Interventional Management of Iliac Lesions

PTA

  • Endovascular treatment of iliac stenoses
    • High technical success rates
    • Low morbidity.
  • Iliac PTA/stenting
    • High rates of patency
    • Improvement in functional outcome for the individual patient
  • Stent placement
    • Balloon expandable stent: Useful in Ostial Lesions
      • Greater radial force
      • Allow greater precision for placement
    • Self-expandable stent
      • Longer lesions in which the proximal vessel maybe several millimeters larger than the distal vessel
      • Used predominantly in common iliac artery orificial occlusions

Surgical

Complications

  • Intraoperative complications
  • Dissection
  • Extravasation
  • Arterial rupture
  • Postoperative complications
  • Pseudoaneurysm formation at the access site
  • Distal embolization
  • Hematoma

Prognosis

  • Ideal Iliac PTA Lesions
    • Stenotic lesion
    • Non-calcified
    • Discrete (< 3cm)
    • Patent run – off vessels (> 2)
    • Non- diabetic patients
  • Predictors of long-term failure
    • Clinical status: CLI vs claudicant
    • Smoking
    • Women?
    • Vessel diameter < 8mm
    • Outflow status
    • Lack of antiplatelet regimen
    • Number of stents
    • Occlusion vs. stenosis

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