Warthin's tumor pathophysiology

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Warthin's tumor Microchapters
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Patient Information
Overview
Historical Perspective
Pathophysiology
Causes
Differentiating Warthin's tumor from other Diseases
Epidemiology and Demographics
Risk Factors
Natural History, Complications and Prognosis
Diagnosis
History and Symptoms
Physical Examination
Laboratory Findings
CT
MRI
Echocardiography or Ultrasound
Other Imaging Findings
Biopsy
Treatment
Surgery
Cost-Effectiveness of Therapy
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Case #1
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Overview

The appearance of this tumor under the microscope is unique. There are cystic spaces surrounded by two uniform rows of cells with centrally placed pyknotic nuclei. The cystic spaces have epithelium referred to as papillary infoldings that protude into them. Additionally, the epithelium has lymphoid stroma with germinal center formation.

Images

Histopathology of Warthin tumor in the parotid gland. H&E stain.

Histopathology of Warthin tumor in the parotid gland. Another view of a file "Warthin tumor (1).jpg". H&E stain.

Histopathology of Warthin tumor in the parotid gland. Higher magnification of a file "Warthin tumor (1).jpg". H&E stain.