Renal cell carcinoma CT

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Overview

Radiology

Radiology

The characteristic appearance of renal cell carcinoma (RCC) is a solid renal lesion which disturbs the renal contour. It will frequently have an irregular or lobulated margin. 85% of solid renal masses will be RCC. 10% of RCC will contain calcifications, and some contain macroscopic fat (likely due to invasion and encasement of the perirenal fat). Following intravenous contrast administration (computed tomography or magnetic resonance imaging), enhancement will be noted, and will increase the conspicuity of the tumor relative to normal renal parenchyma.

Patient #1

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T2: Renal cell carcinoma with intravascular extension


T1 post contrast: Renal cell carcinoma with intravascular extension


T1 post contrast: Renal cell carcinoma with intravascular extension


T1 post contrast: Renal cell carcinoma with intravascular extension


T1 post contrast: Renal cell carcinoma with intravascular extension


Patient #2

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Large renal cell carcinoma


Large renal cell carcinoma


Large renal cell carcinoma


Patient #3

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Non contrast: Renal cell carcinoma


Non contrast: Renal cell carcinoma


Renal cell carcinoma


Renal cell carcinoma


Patient #4

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Renal cell carcinoma


Renal cell carcinoma


Renal cell carcinoma


Renal cell carcinoma


Renal cell carcinoma


At diagnosis, 30% of renal cell carcinoma has spread to that kidney's renal vein, and 5-10% has continued on into the inferior vena cava[1].

Percutaneous biopsy can be performed by a radiologist using ultrasound or computed tomography to guide sampling of the tumor for the purpose of diagnosis. However this is not routinely performed because when the typical imaging features of renal cell carcinoma are present, the possibility of an incorrectly negative result together with the risk of a medical complication to the patient make it unfavorable from a risk-benefit perspective.This is not completely accurate, there are new experimental treatments.

A CT scan showing bilateral renal cell carcinomas


References

  1. Oto A, Herts BR, Remer EM, Novick AC. Inferior vena cava tumor thrombus in renal cell carcinoma: staging by MR imaging and impact on surgical treatment. AJR Am J Roentgenol. 1998 Dec;171(6):1619-24. PMID 9843299.