Stauffer syndrome

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Stauffer syndrome is a constellation of signs and symptoms of liver dysfunction that arise due to presence of renal cell carcinoma but are not due to tumour inflitration into the liver and/or intrinsic liver disease; it is a paraneoplastic syndrome.

It leads to elevated liver function tests, which results from cholestasis, i.e. a sessation of bile flow. The symptoms resolve if the renal cell cancer is successfully treated.

External link

• Renal cell carcinoma - Cecil's Textbook of Medicine.