Mononucleosis pathophysiology
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Mononucleosis Microchapters |
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Mononucleosis pathophysiology On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Transmission
- Saliva
- Epstein-Barr virus (EBV) shed for up to 18 months after primary infection
- Intermittent viral shedding thereafter in asymptomatic sero+ patients
- Increased viral shedding in immunocompromised patients
- Blood transfusion (rare)
Mononucleosis is typically transmitted from asymptomatic individuals through saliva, earning it the name "the kissing disease", or by sharing a drink, or sharing eating utensils. It may also be transmitted through blood. Individuals in close living arrangements nearly always pass the infection onto each other, although symptoms may not present for months or even years. As with many viral infections, such as chicken pox, antibodies are developed by individuals who become infected with the disease and recover. In most individuals, these antibodies remain in their system, creating lifelong immunity to further infections.[1]
References
- ↑ "Mononucleosis -- Causes". eMedicineHealth. 12/7/2007. Retrieved 2008-03-01. Check date values in:
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