Smallpox differential diagnosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Michael Maddaleni, B.S.
Overview
In the past, chickenpox was regularly mistaken for smallpox. Pustular scarring that can be seen in the face is a common symptom of both infections. Many times herpes zoster and erythema multiforme produce a vesicular rash and fever that has been confused with smallpox.
Conditions to consider
- Insect bites
- Acute leukemia
- Secondary syphilis
- Infectious mononucleosis
- Toxic erythemas
- Parvovirus B19
- Drug eruptions