Monocytosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Varun Kumar, M.B.B.S. [2]

Overview

Monocytosis is an increase in the number of circulating monocytes. In humans, 950/μL is regarded as at the upper limit of normal; monocyte counts above this level are regarded as monocytosis. [1] Monocytes are white blood cells that give rise to macrophages and dendritic cells in the immune system.

Differential Diagnosis of Causes of Monocytosis

By Organ System

Cardiovascular Bacterial Endocarditis
Chemical / poisoning No underlying causes
Dermatologic No underlying causes
Drug Side Effect No underlying causes
Ear Nose Throat No underlying causes
Endocrine Sarcoidosis
Environmental Brucellosis, Kala-azar, Listeriosis, Rocky Mountain spotted fever
Gastroenterologic Cirrhosis, Crohn's disease, Infectious hepatitis, Inflammatory bowel disease, Irritable Bowel Syndrome, Sarcoidosis, Ulcerative colitis
Genetic Gaucher's Disease, Kostmann syndrome, Sarcoidosis
Hematologic Acute lymphocytic leukemia, Benign familial neutropenia, Chronic myeloid leukaemia, Chronic neutropenia, Cyclical neutropenia, Granulocyte-macrophage colony stimulating factor, Hodgkin lymphoma, Kostmann syndrome, Lymphoproliferative disease, Myelodysplastic syndrome, Myeloma, Myeloproliferative disease, Polyarteritis nodosa, Recovery from neutropenia, Visceral leishmaniasis
Iatrogenic No underlying causes
Infectious Disease Bacterial Endocarditis, Brucellosis, Cytomegalovirus, Herpes Zoster Virus, Infectious Endocarditis, Infectious hepatitis, Kala-azar, Listeriosis, Malaria, Mononeucleosis, Mycobacterium tuberculosis, Relapsing fever, Rocky Mountain spotted fever, Syphillis, Trypanosomiasis, Whooping cough
Musculoskeletal / Ortho Rheumatoid arthritis
Neurologic No underlying causes
Nutritional / Metabolic Gaucher's Disease, Lipid storage disease
Obstetric/Gynecologic No underlying causes
Oncologic Acute lymphocytic leukemia, Chronic myeloid leukaemia, Hodgkin lymphoma, Myeloproliferative disease, Non-Hodgkin lymphoma, Other malignant lymphomas
Opthalmologic No underlying causes
Overdose / Toxicity No underlying causes
Psychiatric No underlying causes
Pulmonary Mycobacterium tuberculosis, Whooping cough
Renal / Electrolyte No underlying causes
Rheum / Immune / Allergy Crohn's disease, Inflammatory bowel disease, Irritable Bowel Syndrome, Polyarteritis nodosa, Rheumatoid arthritis, Sarcoidosis, Systemic lupus erythematosus, Ulcerative colitis
Sexual Syphillis
Trauma No underlying causes
Urologic No underlying causes
Miscellaneous Kala-azar

In Alphabetical Order

References

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