Pituitary tumour
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Pituitary tumour
- Growth hormone (GH)
- Prolactin (PRL)
- Thyroid-stimulating hormone (TSH)
- Adrenocorticotropic hormone (ACTH)
- Melanocyte-stimulating hormone (MSH)
- Follicle stimulating hormone (FSH)
- Luteinizing hormone (LH)
- Although theoretically a tumour could secrete any of these hormones, the common tumours secrete growth hormone (see acromegaly), prolactin (see prolactinoma and hyperprolactinaemia), mixed secretions or no secretion at all.
Diagnosis
- Once tumours were categorised by their light microscopic appearance but now tumours are more reliably categorised by immunoperoxidase studies.
- Blood tests for the hormones are important diagnostic tools.
- CT scans, MRI and other imaging techniques are important for determining size (and seriousness of tumours), growth over time and treatment options.
Treatment
Treatment includes:
- Bromocriptine
- Surgical removal
- Ablation by radiotherapy
Prognosis
Most tumours are benign but are quite serious because of their position close to important brain structures.