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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Weight gain is an increase in body weight. It is generally caused by the intake of excess calories, little exercise, or may be caused by a medical condition. One exception is bodybuilding, in which muscle is gained by workout routines. With a large differential diagnosis, weight gain is a prevalent complaint among adult patients.
It may be intentional or unintentional, sometimes for muscle building, or for health reasons, i.e. increasing body fat percentage to a healthy amount. Intentional reasons may include gaining weight to get to a healthy weight, bodybuilding, and recovery for eating disorders like Anorexia Nervousa.
See also obesity for a full discussion.
Symptoms
Causes
Common Causes
Causes by Organ System
(By organ system)
Cardiovascular
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Alstrom syndrome, Heart failure
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Chemical / poisoning
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No underlying causes
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Dermatologic
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Hypertrichosis brachydactyly obesity and mental retardation
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Drug Side Effect
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4-Chlorodehydromethyltestosterone, Aldesleukin , Amiodarone, Amisulpride, Amitriptyline, Anastrozole , Aripiprazole , Asenapine, Atenolol, Azelastine, Bisoprolol , Bosentan , Carteolol , Carvedilol , Chlorpropamide, Chlorprothixene, Ciprofloxacin, Clomiphene , Clomipramine, Clozapine, Combined oral contraceptive pill, Cyclosporine , Cyproheptadine, Cyproterone, Danazol, Desonide, Desoximetasone , Dexamethasone, Diclofenac, Dienogest, Diflunisal , Disopyramide, Docetaxel , Doxazosin , Doxepin, Escitalopram, Estrogen Injection, Ethinylestradiol, Etodolac , Fenoprofen , Fentanyl, Fludrocortisone acetate , Gabapentin, Gestrinone, Glatiramer, Glucocorticoid, Goserelin, Haloperidol, Hormone replacement therapy, Hydralazine , Hydrochlorothiazide, Hydrocortisone, Iloperidone, Imatinib, Imipramine, Implanon, Indomethacin, Insulin, Interferon beta-1a , Interferon beta-1b , Itraconazole, Ketorolac, Ketotifen, Labetalol, Levobunolol, Levomepromazine, Lithium , Lofepramine, Maprotiline, Meclofenamate, Medroxyprogesterone, Mefenamic acid, Megestrol , Meglitinide, Mesoridazine, Methylprednisolone, Metoprolol, Mianserin, Minoxidil, Misoprostol, Nabumetone, Nadolol, Nialamide, Norplant, NuvaRing, Olanzapine, Oprelvekin, Oxandrolone, Oxcarbazepine, Oxymetholone, Paliperidone, Paroxetine, Perphenazine, Phenelzine, Phenothiazine, Pindolol, Pioglitazone, Piroxicam, Pizotifen, Prednisolone, Pregabalin, Progesterone, Propranolol, Quetiapine, Ractopamine, Reserpine, Risperidone, Rituximab, Rofecoxib, Rosiglitazone, Salsalate, Sargramostim, Selective serotonin reuptake inhibitors, Sertindole , Sertraline, Sirolimus , St John's wort, Steroid medications, Sulfonylureas, Sulindac, Sunitinib , Temozolomide , Terazosin, Thiazolidinedione, Thioridazine , Thiothixene, Timolol, Trazodone, Trestolone, Tretinoin, Triamcinolone oral, Tricyclic antidepressants, Trifluoperazine, Trifluperidol, Valproic acid, Venlafaxine, Vigabatrin, Ziprasidone, Zotepine
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Ear Nose Throat
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Metaphyseal dysostosis mental retardation conductive deafness
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Endocrine
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Achard-Thiers Syndrome , Acromegaly , Anophthalmia-short stature-obesity, Cushing's syndrome, Diabetes mellitus, Froelich's syndrome, Growth hormone deficiency, Growth Hormone Receptor Deficiency, HAIR-AN Syndrome, Hashimoto's thyroiditis, Hyperpituitarism , Hyperprolactinemia, Hypothalamic tumor, Hypothyroidism, Laron Syndrome , Low Testosterone levels, Lymphomatous thyroiditis , Mauriac syndrome, Polycystic ovary Syndrome, Prediabetes, Pseudocyesis, Renal tubulopathy-diabetes mellitus-cerebellar ataxia, Riedel's thyroiditis, Sub clinical hypothyroidism
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Environmental
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No underlying causes
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Gastroenterologic
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Budd-Chiari syndrome , Cirrhosis of the liver, Functioning pancreatic endocrine tumor, Hepatic veno-occlusive disease, Hepatic veno-occlusive disease-immunodeficiency , Insulinoma
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Genetic
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1p36 deletion syndrome, Carpenter's syndrome, Cohen Syndrome , Klinefelter syndrome , Macrosomia Obesity Macrocephaly Ocular abnormalities syndrome, Maturity onset diabetes of the young, X-linked mental retardation-short stature-obesity, X linked mental retardation-precocious puberty-obesity, Obesity due to congenital leptin deficiency, partial 9p duplication, Prader-Willi syndrome, Pseudohypoparathyroidism, Vasquez Hurst Sotos syndrome , Young Hughes syndrome
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Hematologic
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Lipedema, Lymphatic obstruction, Milroy's syndrome, Paget-Schroeder syndrome
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Iatrogenic
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No underlying causes
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Infectious Disease
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No underlying causes
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Musculoskeletal / Ortho
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No underlying causes
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Neurologic
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No underlying causes
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Nutritional / Metabolic
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No underlying causes
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Obstetric/Gynecologic
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No underlying causes
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Oncologic
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No underlying causes
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Opthalmologic
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No underlying causes
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Overdose / Toxicity
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No underlying causes
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Psychiatric
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No underlying causes
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Pulmonary
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No underlying causes
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Renal / Electrolyte
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No underlying causes
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Rheum / Immune / Allergy
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No underlying causes
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Sexual
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No underlying causes
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Trauma
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No underlying causes
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Urologic
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No underlying causes
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Dental
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No underlying causes
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Miscellaneous
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No underlying causes
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Causes in Alphabetical Order
Causes include; [1] [2]
Acute or chronic Liver Disease
- Decreased hepatic protein production causes a decrease in intravascular oncotic pressure
- Leads to edema, ascites etc.
Congestive Heart Failure
Cushing's Syndrome
- Cortisol levels may be elevated due to
- Adrenocorticotropic hormones secreting adrenal adenoma
- Adrenal hyperplasia
- Adrenocorticotropic hormone secreting ectopic tumor
Diabetes Mellitus
Hyperplasia
Hypothalamic lesions
Growth hormone deficiency
Medication side effects
- Oral contraceptives
- Corticosteroids
- Antidepressants
Premenstrual syndrome
Pregnancy
Pre-eclampsia/Eclampsia
Polycystic Ovary Syndrome
- Hirsutism
- Irregular menstrual cycle
- Insulin resistance
- Obesity
Laboratory Findings
- fasting glucose
- urinealysis
- U&E
- Random cortisol
Primary Prevention
- Low calorie diet and excercise
References
- ↑ Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016
- ↑ Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X
Acknowledgements
The content on this page was first contributed by Editor-In-Chief: C. Michael Gibson, M.S., M.D. [2]
List of contributors:
Suggested Reading and Key General References
Suggested Links and Web Resources
For Patients
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