Cirrhosis differential diagnosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2]
Overview
Differential Diagnosis
| Differential Diagnosis | Useful Findings
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| Alcoholic cirrhosis | History EtOH, AST/ALT > 2
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| Chronic Hepatits C Virus (HCV) | HCV AB
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| Primary Biliary Cirrhosis (PBC) | Elevated alk phos, AMA+
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| Primary sclerosing cholangitis | History inflammatory bowel disease (IBD), ANA or ASMA or P-ANCA+
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| Autoimmune hepatitis | Hypergammaglobulinemia, ANA/ASMA +
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| Chronic Hepatitis B Virus | HBsAg+, HBeAg may be +
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| Hemochromatosis | Family history+, Fe/TIBC and ferritin elevated
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| Wilson’s disease | Family history+, young age, low ceruloplasmin |
| Alpha-1-antitrypsin (AAT) deficiency | Family history+, young age, low serum AAT
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