Modic endplate changes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Modic endplate changes is the classification scheme for signal intensity changes in the bone marrow adjacent to the vertebral endplates in degenerative spine disease.

Classification

• Type 1 changes:

• • Increased marrow signal intensity in T2-weighted MR images and decreased signal intensity in T1-weighted MR images.
  • Fibrovascular tissue in endplates

• Type 2 changes:

• • Increased signal intensity in T1- and T2-weighted MR images.
  • Lipid in endplates

• Type 3 changes:

• • Decreased signal intensity in T1 -and T2-weighted MR images.
  • Endplate sclerosis

Modic Change	T1 Signal	T2 Signal
Type 1	Low	High
Type 2	High	High
Type 3	Low	Low

Type 2 changes at C6-C7

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