Disopyramide detailed information

Disopyramide detailed information
Clinical data
Pregnancy; category	AU: B2 ; US: C (Risk not ruled out) ; ;
Routes of; administration	Oral, intravenous
ATC code	C01BA03 (WHO) ;
Legal status
Legal status	UK: POM (Prescription only) ; US: ℞-only ;
Pharmacokinetic data
Bioavailability	High
Protein binding	50% to 65%; (concentration-dependent)
Metabolism	Hepatic (CYP3A4-mediated)
Elimination half-life	6.7 hours (range 4 to 10 hours)
Excretion	Renal (80%)
Identifiers
	IUPAC name 4-dipropan-2-ylamino-2-phenyl-2-pyridin-2-yl-butanamide;
CAS Number	3737-09-5;
PubChem CID	3114;
DrugBank	APRD00507;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C21H29N3O
Molar mass	339.475 g/mol

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Disopyramide (INN, trade names Norpace® and Rythmodan®) is an antiarrhythmic medication. It is a Class Ia antiarrythmic used in the treatment of ventricular tachycardias. It has no effect on alpha or beta adrenergic receptors.

Clinical data

Pregnancy category	AU: B2 US: C (Risk not ruled out)
Routes of administration	Oral, intravenous
ATC code	C01BA03 (WHO)
Legal status
Legal status	UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Bioavailability	High
Protein binding	50% to 65% (concentration-dependent)
Metabolism	Hepatic (CYP3A4-mediated)
Elimination half-life	6.7 hours (range 4 to 10 hours)
Excretion	Renal (80%)
Identifiers
IUPAC name 4-dipropan-2-ylamino-2-phenyl-2-pyridin-2-yl-butanamide
CAS Number	3737-09-5
PubChem CID	3114
DrugBank	APRD00507
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C₂₁H₂₉N₃O
Molar mass	339.475 g/mol