HLA-A43
major histocompatibility complex (human), class I, A43
| ||
| Alleles | A*4301 | |
| Structure (See HLA-A) | ||
| Symbol(s) | HLA-A | |
| EBI-HLA | A*4301 | |
| Locus | chr.6 6p21.31 | |
HLA-A43 (A43) is an HLA-A serotype. The serotype identifies the more common HLA-A*43 gene products. A43 is a split antigen type of the A10 broad antigen type. A*4301 is believed to have been formed by a single gene conversion between another HLA-A and the A*2601 allele.[1] A43 is more common in Africa. A*4301 is rare.
Serotype
| A*43 | --- | A26 | Sample |
| allele | % | % | size (N) |
| 4301 | 35 | 9 |
A43 frequencies
| freq | ||
| ref. | Population | (%) |
| [3] | South Africa Tswana | 4.9 |
| [3] | South Africian Natal Zulu | 3.0 |
| [3] | China Yunnan Han | 1.2 |
| [3] | Zambia Lusaka | 1.2 |
| [3] | Pakistan Karachi Parsi | 0.6 |
| [3] | India North Delhi | 0.5 |
| [3] | Zimbabwe Harare Shona | 0.4 |
| [3] | Italy | 0.01 |
| [3] | China Shanghai | 0.002 |
References
- ↑ Madrigal JA, Hildebrand WH, Belich MP; et al. (1993). "Structural diversity in the HLA-A10 family of alleles: correlations with serology". Tissue Antigens. 41 (2): 72–80. PMID 8475492.
- ↑ derived from IMGT/HLA
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 3.8 Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens. 61 (5): 403–7. PMID 12753660. External link in
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