Legionellosis laboratory findings
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Laboratory Findings
- Complete blood count and differential count - lymphocytopenia and rarely pancytopenia
- Sputum Gram staining - gram negative rods
- Urine antigen test - the urine antigen test is simple, quick, and very reliable; however it will only detect Legionella pneumophila serogroup #1. If the patient has pneumonia and the test is positive then the patient is considered to have Legionnaires’ disease. Also the urine antigen test will not identify the specific subtyping so it cannot be used to match the patient with the environmental source of infection.
- Antibody test (paired sera) - compare antibody levels to Legionella in two blood samples obtained 3 to 6 weeks apart.
- Serum electrolytes - hyponatremia
- Liver function tests - elevated bilirubin levels
- Urinalysis - proteinuria
References