Secondary adrenal insufficiency

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Secondary adrenal insufficiency
ICD-10	E27.1-E27.4
ICD-9	255.4
eMedicine	emerg/16
MeSH	D000309

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Synonyms and keywords: hypocortisolism; adrenal fatigue; hypoadrenia

Overview

Adrenal insufficiency (or "hypocortisolism") is the inability of the adrenal gland to produce adequate amounts of cortisol in response to stress. See also: Adrenal Fatigue or Hypoadrenia.

Causes

• Acute adrenal insufficiency
  • Addison's disease (autoimmune adrenalitis)
  • Septic shock
  • Waterhouse-Friderichsen syndrome
  • Addisonian crisis in case of:
    • Discontinuing corticosteroid therapy without tapering the dosage
    • Surgery, illness or any other form of stress in patients with long-term corticosteroid therapy
• Chronic adrenal insufficiency
  • Addison's disease
  • Congenital Adrenal Hyperplasia
  • Antiphospholipid syndrome
  • Haemochromatosis

See also

• Cushing's syndrome
• Insulin tolerance test
• ACTH stimulation test

External links

• Penn State
• CongenitalAdrenalHyperplasia.org