Drug allergy causes

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Charmaine Patel, M.D. [2]

Drug Allergy
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Overview

The types of drugs that can cause drug allergies vary. Drugs containing sulfa are common in causing drug allergy.

Causes

Common Causes

When a medication causes an allergic reaction, it is called an allergen. The following is a short list of the most common drug allergens

• Antibiotics
  • Penicillin
  • Sulfa drugs
  • Tetracycline
• Analgesics
  • Codeine
  • Non-steroidal anti-inflammatory drugs (NSAIDs)
• Antiseizure
  • Dilantin
  • Tegretol

Causes by Organ System

Cardiovascular	No underlying causes
Chemical / poisoning	No underlying causes
Dermatologic	No underlying causes
Drug Effect	Barbiturates, sulfonylurea, sulfonamide, acetazolamide, allopurinol, amifostine, benoxaprofen, brentuximab vedotin, carbamazepine, chlorambucil, chlormezanone, clindamycin,codeine, diclofenac, diltiazem, erlotinib, ethotoin, etravirine, fosamprenavir, ibritunomab tiuxetan, iplimumab, isoniazid, lamotrigine, leflunomide, lenalidomide,methylphenidate, nevirapine, NSAIDs, penicillamine, phenobarbitol, phenylbutazone, phenytoin, primidone, procainamide, sorafanib, streptomycin, sulfasalazine, suramin, terbanafine, tetracycline, thiabendazole, thiacetazone, vancomycin, vandetanib, zonesamib
Ear Nose Throat	No underlying causes
Endocrine	No underlying causes
Environmental	No underlying causes
Gastroenterologic	No underlying causes
Genetic	No underlying causes
Hematologic	No underlying causes
Iatrogenic	No underlying causes
Infectious Disease	Histoplasmosis, mycoplasma pneumoniae, staphylococcal scalded skin syndrome, staphylococcus aureus, herpes simplex virus 1, herpes simplex virus 2
Musculoskeletal / Ortho	No underlying causes
Neurologic	No underlying causes
Nutritional / Metabolic	No underlying causes
Obstetric/Gynecologic	No underlying causes
Oncologic	No underlying causes
Opthalmologic	No underlying causes
Overdose / Toxicity	No underlying causes
Psychiatric	No underlying causes
Pulmonary	No underlying causes
Renal / Electrolyte	No underlying causes
Rheum / Immune / Allergy	Systemic lupus erythematosus
Sexual	No underlying causes
Trauma	No underlying causes
Urologic	No underlying causes
Miscellaneous	No underlying causes