N-Acetylglutamic acid
Overview
N-Acetylglutamic acid (abbreviated NAcGlu) is biosynthesized from glutamic acid and acetyl-CoA by the enzyme N-acetylglutamate synthase. Arginine is the activator for this reaction.
The reverse reaction, hydrolysis of the acetyl group, is catalyzed by a specific hydrolase.
NAcGlu activates carbamoyl phosphate synthase in the urea cycle.
