Mitral valve prolapse natural history, complications and prognosis
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Mitral valve prolapse Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Complications
Mitral regurgitation
Mitral valve prolapse is frequently associated with mild mitral regurgitation,[1] where blood aberrantly flows from the left ventricle into the left atrium during systole. Occasionally MVP patients experience severe regurgitation, often due to chordae tendineae rupture.[2]
Sudden death
Severe mitral valve prolapse is associated with arrhythmias and atrial fibrillation that may progress and lead to sudden death. As there is no evidence that a prolapsed valve itself contributes to such arrythmias,[3] these complications are more likely due to mitral regurgitation and congestive heart failure.
Prognosis
The major predictors of mortality are the severity of mitral regurgitation and the ejection fraction.[4] Generally, MVP is a benign disorder. However, MVP patients with a murmur, not just an isolated click, may have a poorer prognosis.
References
- ↑ Kolibash AJ (1988). "Progression of mitral regurgitation in patients with mitral valve prolapse". Herz. 13 (5): 309–17. PMID 3053383.
- ↑ Tanser, Paul H. (March 2007). "Mitral Valve Prolapse (MVP)". Merck. Retrieved 2007-07-11.
- ↑
- ↑ Rodgers, Ellie (May 11, 2004). "Mitral Valve Regurgitation". Healthwise, on Yahoo. Retrieved 2007-07-11.