Dilated cardiomyopathy causes
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-in-Chief: Sachin Shah, M.D.
Overview
Causes
Common Causes
There are many causes and there are varying degrees of severity of the disease. Some forms are reversible and some are irreversible; some patients may be completely asymptoamtic and some may require cardiac transplantation.
There are many causes of dilated cardiomyopathy.
- Idiopathic-most common and it accounts for roughly 50% of cases.[1]
- Myocarditis-next most common and it accounts for roughly 10% of cases.
- Ischemic cardiomyopathy
- Infiltrative disease
- Hypertensive heart disease
- Substance abuse (i.e. alcohol abuse or cocaine abuse)
- Connective tissue disease
- Peripartum cardiomyopathy
- Drugs (such as the chemotherapeutic agent doxarubacin)
- HIV infection
- Antiretroviral drugs
- Toxins (such as cobalt, lead or beryllium)
- Nutritional deficiencies (such as thiamine or selenium).
The high percentage of idiopathic dilated cardiomyopathy may be related to the difficulty in diagnosing viral myocarditis.
References
- ↑ Felker GM, Thompson RE, et al. Underlying causes and long-term survival in patients with initially unexplained cardiomyopathy. N Engl J Med 2000 Apr 13;342(14):1077-84.