Hypothyroidism classification

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Hypothyroidism Main page

Patient Information

Overview

Classification

Primary hypothyroidism
Hashimoto's thyroiditis
Secondary hypothyroidism
Tertiary hypothyroidism

Differentiating different causes of hypothyroidism

Screening

Diagnosis

History and symptoms

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Classification

Hypothyroidism is often classified by the organ of origin:[1][2]

Type Origin Description
Primary hypothyroidism thyroid gland The most common forms include Hashimoto's thyroiditis (an autoimmune disease) and radioiodine therapy for hyperthyroidism.
Secondary hypothyroidism pituitary gland Occurs if the pituitary gland does not create enough thyroid stimulating hormone (TSH, Thyrotropin) to induce the thyroid gland to create a sufficient quantity of thyroxine. Although not every case of secondary hypothyroidism has a clear-cut cause, it is usually caused when the pituitary is damaged by a tumor, radiation, or surgery so that it is no longer able to instruct the thyroid to make enough hormone[3]
Tertiary hypothyroidism, also called hypothalamic-pituitary-axis hypothyroidism hypothalamus Results when the hypothalamus fails to produce sufficient TRH.

References

  1. http://www.umm.edu/patiented/articles/what_causes_hypothyroidism_000038_2.htm
  2. http://www.pathology.vcu.edu/education/endocrine/endocrine/pituitary/diseases.html
  3. American Thyroid Association (ATA) (2003). Hypothyroidism Booklet (PDF). p. 6.