Cushing's syndrome natural history, complications and prognosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Natural History
Complications
- Insulin resistance (especially common in ectopic ACTH production), leading to hyperglycemia (high blood sugars) which can lead to diabetes mellitus.
- Untreated Cushing's syndrome can lead to heart disease and increased mortality.
Prognosis
The prognosis for those with Cushing's syndrome varies depending on the cause of the disease. Most cases of Cushing's syndrome can be cured. Many individuals with Cushing's syndrome show significant improvement with treatment, although some may find recovery complicated by various aspects of the causative illness. Some kinds of tumors may recur.