Long QT Syndrome natural history, complications and prognosis

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Risk calculators and risk factors for Long QT Syndrome natural history, complications and prognosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [2]

Natural History, Complications and Prognosis

Risk stratification

The risk for untreated LQTS patients having events (syncopes or cardiac arrest) can be predicted from their genotype (LQT1-8), gender and corrected QT interval.

• High risk (>50%)

QTc>500 msec LQT1 & LQT2 & LQT3(males)

• Intermediate risk (30-50%)

QTc>500 msec LQT3(females)

QTc<500 msec LQT2(females)& LQT3

• Low risk (<30%)

QTc<500 msec LQT1 & LQT2 (males)