Acute lymphoblastic leukemia epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2]

Epidemiology and Demographics

Incidence

• The number of annual ALL cases in the US is roughly 4000, 3000 of which inflict children.
• There is an increased incidence in people with Down's Syndrome, Fanconi's anemia, Bloom's syndrome, ataxia-telangiectasia, X-linked agammaglobulinemia and severe combined immunodeficiency.

Age

• ALL accounts for approximately 80 percent of all childhood leukemia cases, making it the most common type of childhood cancer.
• It has a peak incident rate of 2-5 years old, decreasing in incidence with increasing age before increasing again at around 50 years old.

Gender

• ALL is slightly more common in males than females.