Typhus natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Prognosis

Without treatment, death may occur in 10 - 60% of patients with epidemic typhus. Patients over age 60 have the highest risk of death. Patients who receive treatment quickly should completely recover. Less than 2% of untreated patients with murine typhus may die. Prompt antibiotic treatment will cure nearly all patients.

Possible complications include:

• Renal insufficiency
• Pneumonia
• Central nervous system damage