Acute viral nasopharyngitis natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Natural History

After initial infection, the viral replication cycle begins within 8 to 12 hours. Symptoms can occur shortly thereafter, and usually begin within 2 to 5 days after infection, although occasionally in as little as 10 hours after infection.

Complications

The common cold can lead to

• Opportunistic coinfections or superinfections such as
• Acute bronchitis,
• Bronchiolitis,
• Croup,
• pneumonia,
• Sinusitis,
• Otitis media,
• Strep throat.

People with chronic lung diseases such as asthma and COPD are especially vulnerable. Colds may cause acute exacerbations of asthma, emphysema or chronic bronchitis.