ADCY1
| Adenylate cyclase 1 (brain) | |||||||||||
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| Symbols | ADCY1 ; | ||||||||||
| External IDs | Template:OMIM5 Template:MGI HomoloGene: 41419 | ||||||||||
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| Species | Human | Mouse | |||||||||
| Entrez | n/a | n/a | |||||||||
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| RefSeq (mRNA) | n/a | n/a | |||||||||
| RefSeq (protein) | n/a | n/a | |||||||||
| Location (UCSC) | n/a | n/a | |||||||||
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Adenylate cyclase 1 (brain), also known as ADCY1, is a human gene.[1]
This gene encodes a form of adenylate cyclase expressed in brain. A similar protein in mouse is involved in pattern formation of the brain.[1]
References
Further reading
- Osawa S, Dhanasekaran N, Woon CW, Johnson GL (1990). "G alpha i-G alpha s chimeras define the function of alpha chain domains in control of G protein activation and beta gamma subunit complex interactions". Cell. 63 (4): 697–706. PMID 2121366.
- Gaudin C, Homcy CJ, Ishikawa Y (1994). "Mammalian adenylyl cyclase family members are randomly located on different chromosomes". Hum. Genet. 94 (5): 527–9. PMID 7959689.
- Villacres EC, Xia Z, Bookbinder LH; et al. (1993). "Cloning, chromosomal mapping, and expression of human fetal brain type I adenylyl cyclase". Genomics. 16 (2): 473–8. doi:10.1006/geno.1993.1213. PMID 8314585.
- Whisnant RE, Gilman AG, Dessauer CW (1996). "Interaction of the two cytosolic domains of mammalian adenylyl cyclase". Proc. Natl. Acad. Sci. U.S.A. 93 (13): 6621–5. PMID 8692867.
- Barcova M, Speth C, Kacani L; et al. (1999). "Involvement of adenylate cyclase and p70(S6)-kinase activation in IL-10 up-regulation in human monocytes by gp41 envelope protein of human immunodeficiency virus type 1". Pflugers Arch. 437 (4): 538–46. PMID 10089566.
- Speth C, Joebstl B, Barcova M, Dierich MP (2000). "HIV-1 envelope protein gp41 modulates expression of interleukin-10 and chemokine receptors on monocytes, astrocytes and neurones". AIDS. 14 (6): 629–36. PMID 10807185.
- Patke CL, Shearer WT (2000). "gp120- and TNF-alpha-induced modulation of human B cell function: proliferation, cyclic AMP generation, Ig production, and B-cell receptor expression". J. Allergy Clin. Immunol. 105 (5): 975–82. doi:10.1067/mai.2000.105315. PMID 10808179.
- Patrizio M, Colucci M, Levi G (2001). "Human immunodeficiency virus type 1 Tat protein decreases cyclic AMP synthesis in rat microglia cultures". J. Neurochem. 77 (2): 399–407. PMID 11299302.
- Côté M, Guillon G, Payet MD, Gallo-Payet N (2001). "Expression and regulation of adenylyl cyclase isoforms in the human adrenal gland". J. Clin. Endocrinol. Metab. 86 (9): 4495–503. PMID 11549699.
- Speth C, Schabetsberger T, Mohsenipour I; et al. (2002). "Mechanism of human immunodeficiency virus-induced complement expression in astrocytes and neurons". J. Virol. 76 (7): 3179–88. PMID 11884542.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Ludwig MG, Seuwen K (2003). "Characterization of the human adenylyl cyclase gene family: cDNA, gene structure, and tissue distribution of the nine isoforms". J. Recept. Signal Transduct. Res. 22 (1–4): 79–110. PMID 12503609.
- Scherer SW, Cheung J, MacDonald JR; et al. (2003). "Human chromosome 7: DNA sequence and biology". Science. 300 (5620): 767–72. doi:10.1126/science.1083423. PMID 12690205.
- Tucholski J, Johnson GV (2003). "Tissue transglutaminase directly regulates adenylyl cyclase resulting in enhanced cAMP-response element-binding protein (CREB) activation". J. Biol. Chem. 278 (29): 26838–43. doi:10.1074/jbc.M303683200. PMID 12743114.
- Hillier LW, Fulton RS, Fulton LA; et al. (2003). "The DNA sequence of human chromosome 7". Nature. 424 (6945): 157–64. doi:10.1038/nature01782. PMID 12853948.
- Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Wang H, Ferguson GD, Pineda VV; et al. (2004). "Overexpression of type-1 adenylyl cyclase in mouse forebrain enhances recognition memory and LTP". Nat. Neurosci. 7 (6): 635–42. doi:10.1038/nn1248. PMID 15133516.
- Vortherms TA, Nguyen CH, Berlot CH, Watts VJ (2005). "Using molecular tools to dissect the role of Galphas in sensitization of AC1". Mol. Pharmacol. 66 (6): 1617–24. doi:10.1124/mol.104.000166. PMID 15361543.
- Weber B, Schaper C, Scholz J; et al. (2006). "Interaction of the amyloid precursor like protein 1 with the alpha2A-adrenergic receptor increases agonist-mediated inhibition of adenylate cyclase". Cell. Signal. 18 (10): 1748–57. doi:10.1016/j.cellsig.2006.01.017. PMID 16531006.
- Nlend MC, Schmid A, Sutto Z; et al. (2007). "Calcium-mediated, purinergic stimulation and polarized localization of calcium-sensitive adenylyl cyclase isoforms in human airway epithelia". FEBS Lett. 581 (17): 3241–6. doi:10.1016/j.febslet.2007.06.015. PMID 17586501.
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