AP1M2

Adaptor-related protein complex 1, mu 2 subunit
Identifiers
Symbols	AP1M2 ; HSMU1B; MU-1B; MU1B
External IDs	Template:OMIM5 Template:MGI HomoloGene: 55906
Gene ontology Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Adaptor-related protein complex 1, mu 2 subunit, also known as AP1M2, is a human gene.

This gene encodes a subunit of the heterotetrameric adaptor-related protein comlex 1 (AP-1), which belongs to the adaptor complexes medium subunits family. This protein is capable of interacting with tyrosine-based sorting signals.

Further reading

• Hirst J, Robinson MS (1998). "Clathrin and adaptors". Biochim. Biophys. Acta. 1404 (1–2): 173–93. PMID 9714795.
• Ohno H, Stewart J, Fournier MC; et al. (1995). "Interaction of tyrosine-based sorting signals with clathrin-associated proteins". Science. 269 (5232): 1872–5. PMID 7569928.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. PMID 8125298.
• Seaman MN, Sowerby PJ, Robinson MS (1996). "Cytosolic and membrane-associated proteins involved in the recruitment of AP-1 adaptors onto the trans-Golgi network". J. Biol. Chem. 271 (41): 25446–51. PMID 8810314.CS1 maint: Multiple names: authors list (link)
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K; et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. PMID 9373149.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Stephens DJ, Banting G (1998). "Specificity of interaction between adaptor-complex medium chains and the tyrosine-based sorting motifs of TGN38 and lgp120". Biochem. J. 335 ( Pt 3): 567–72. PMID 9794796.
• Berlioz-Torrent C, Shacklett BL, Erdtmann L; et al. (1999). "Interactions of the cytoplasmic domains of human and simian retroviral transmembrane proteins with components of the clathrin adaptor complexes modulate intracellular and cell surface expression of envelope glycoproteins". J. Virol. 73 (2): 1350–61. PMID 9882340.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ohno H, Tomemori T, Nakatsu F; et al. (1999). "Mu1B, a novel adaptor medium chain expressed in polarized epithelial cells". FEBS Lett. 449 (2–3): 215–20. PMID 10338135.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Fölsch H, Ohno H, Bonifacino JS, Mellman I (1999). "A novel clathrin adaptor complex mediates basolateral targeting in polarized epithelial cells". Cell. 99 (2): 189–98. PMID 10535737.CS1 maint: Multiple names: authors list (link)
• Nakatsu F, Kadohira T, Gilbert DJ; et al. (2000). "Genomic structure and chromosome mapping of the genes encoding clathrin-associated adaptor medium chains mu1A (Ap1m1) and mu1B (Ap1m2)". Cytogenet. Cell Genet. 87 (1–2): 53–8. PMID 10640811.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Umeda A, Meyerholz A, Ungewickell E (2000). "Identification of the universal cofactor (auxilin 2) in clathrin coat dissociation". Eur. J. Cell Biol. 79 (5): 336–42. PMID 10887964.CS1 maint: Multiple names: authors list (link)
• Fölsch H, Pypaert M, Schu P, Mellman I (2001). "Distribution and function of AP-1 clathrin adaptor complexes in polarized epithelial cells". J. Cell Biol. 152 (3): 595–606. PMID 11157985.CS1 maint: Multiple names: authors list (link)
• Wyss S, Berlioz-Torrent C, Boge M; et al. (2001). "The highly conserved C-terminal dileucine motif in the cytosolic domain of the human immunodeficiency virus type 1 envelope glycoprotein is critical for its association with the AP-1 clathrin adaptor [correction of adapter]". J. Virol. 75 (6): 2982–92. doi:10.1128/JVI.75.6.2982-2992.2001. PMID 11222723.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ohka S, Ohno H, Tohyama K, Nomoto A (2001). "Basolateral sorting of human poliovirus receptor alpha involves an interaction with the mu1B subunit of the clathrin adaptor complex in polarized epithelial cells". Biochem. Biophys. Res. Commun. 287 (4): 941–8. doi:10.1006/bbrc.2001.5660. PMID 11573956.CS1 maint: Multiple names: authors list (link)
• Korolchuk VI, Banting G (2003). "CK2 and GAK/auxilin2 are major protein kinases in clathrin-coated vesicles". Traffic. 3 (6): 428–39. PMID 12010461.
• Collins BM, McCoy AJ, Kent HM; et al. (2002). "Molecular architecture and functional model of the endocytic AP2 complex". Cell. 109 (4): 523–35. PMID 12086608.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Sugimoto H, Sugahara M, Fölsch H; et al. (2003). "Differential recognition of tyrosine-based basolateral signals by AP-1B subunit mu1B in polarized epithelial cells". Mol. Biol. Cell. 13 (7): 2374–82. doi:10.1091/mbc.E01-10-0096. PMID 12134076.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)