ASF1B
| ASF1 anti-silencing function 1 homolog B (S. cerevisiae) | |||||
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| Identifiers | |||||
| Symbols | ASF1B ; CIA-II; FLJ10604 | ||||
| External IDs | Template:OMIM5 Template:MGI HomoloGene: 56797 | ||||
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| RNA expression pattern | |||||
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| Species | Human | Mouse | |||
| Entrez | n/a | n/a | |||
| Ensembl | n/a | n/a | |||
| UniProt | n/a | n/a | |||
| RefSeq (mRNA) | n/a | n/a | |||
| RefSeq (protein) | n/a | n/a | |||
| Location (UCSC) | n/a | n/a | |||
| PubMed search | n/a | n/a | |||
ASF1 anti-silencing function 1 homolog B (S. cerevisiae), also known as ASF1B, is a human gene.[1]
This gene encodes a member of the H3/H4 family of histone chaperone proteins and is similar to the anti-silencing function-1 gene in yeast. The encoded protein is the substrate of the tousled-like kinase family of cell cycle-regulated kinases, and may play a key role in modulating the nucleosome structure of chromatin by ensuring a constant supply of histones at sites of nucleosome assembly.[1]
References
Further reading
- Loyola A, Almouzni G (2004). "Histone chaperones, a supporting role in the limelight". Biochim. Biophys. Acta. 1677 (1–3): 3–11. doi:10.1016/j.bbaexp.2003.09.012. PMID 15020040.
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. PMID 8125298.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K; et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. PMID 9373149.
- Silljé HH, Nigg EA (2001). "Identification of human Asf1 chromatin assembly factors as substrates of Tousled-like kinases". Curr. Biol. 11 (13): 1068–73. PMID 11470414.
- Mello JA, Silljé HH, Roche DM; et al. (2002). "Human Asf1 and CAF-1 interact and synergize in a repair-coupled nucleosome assembly pathway". EMBO Rep. 3 (4): 329–34. doi:10.1093/embo-reports/kvf068. PMID 11897662.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Umehara T, Horikoshi M (2003). "Transcription initiation factor IID-interactive histone chaperone CIA-II implicated in mammalian spermatogenesis". J. Biol. Chem. 278 (37): 35660–7. doi:10.1074/jbc.M303549200. PMID 12842904.
- Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Brandenberger R, Wei H, Zhang S; et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197.
- Groth A, Ray-Gallet D, Quivy JP; et al. (2005). "Human Asf1 regulates the flow of S phase histones during replicational stress". Mol. Cell. 17 (2): 301–11. doi:10.1016/j.molcel.2004.12.018. PMID 15664198.
- Sen SP, De Benedetti A (2006). "TLK1B promotes repair of UV-damaged DNA through chromatin remodeling by Asf1". BMC Mol. Biol. 7: 37. doi:10.1186/1471-2199-7-37. PMID 17054786.
- Hayashi R, Goto Y, Tanaka R; et al. (2007). "Transcriptional regulation of human chromatin assembly factor ASF1". DNA Cell Biol. 26 (2): 91–9. doi:10.1089/dna.2006.0515. PMID 17328667.
- Ewing RM, Chu P, Elisma F; et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931.
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