BANP
BTG3 associated nuclear protein | |||||
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Identifiers | |||||
Symbols | BANP ; DKFZp761H172; FLJ10177; FLJ20538; SMAR1; SMARBP1 | ||||
External IDs | Template:MGI HomoloGene: 9635 | ||||
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Orthologs | |||||
Template:GNF Ortholog box | |||||
Species | Human | Mouse | |||
Entrez | n/a | n/a | |||
Ensembl | n/a | n/a | |||
UniProt | n/a | n/a | |||
RefSeq (mRNA) | n/a | n/a | |||
RefSeq (protein) | n/a | n/a | |||
Location (UCSC) | n/a | n/a | |||
PubMed search | n/a | n/a |
BTG3 associated nuclear protein, also known as BANP, is a human gene.[1]
This gene encodes a protein that binds to matrix attachment regions. The protein functions as a tumor suppressor and cell cycle regulator. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.[1]
References
Further reading
- Hillier LD, Lennon G, Becker M; et al. (1997). "Generation and analysis of 280,000 human expressed sequence tags". Genome Res. 6 (9): 807–28. PMID 8889549.
- Birot A, Duret L, Bartholin L; et al. (2000). "Identification and molecular analysis of BANP". Gene. 253 (2): 189–96. PMID 10940556.
- Chattopadhyay S, Kaul R, Charest A; et al. (2001). "SMAR1, a novel, alternatively spliced gene product, binds the Scaffold/Matrix-associated region at the T cell receptor beta locus". Genomics. 68 (1): 93–6. doi:10.1006/geno.2000.6279. PMID 10950932.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Kaul R, Mukherjee S, Ahmed F; et al. (2003). "Direct interaction with and activation of p53 by SMAR1 retards cell-cycle progression at G2/M phase and delays tumor growth in mice". Int. J. Cancer. 103 (5): 606–15. doi:10.1002/ijc.10881. PMID 12494467.
- Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Brandenberger R, Wei H, Zhang S; et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197.
- Kaul-Ghanekar R, Jalota A, Pavithra L; et al. (2004). "SMAR1 and Cux/CDP modulate chromatin and act as negative regulators of the TCRbeta enhancer (Ebeta)". Nucleic Acids Res. 32 (16): 4862–75. doi:10.1093/nar/gkh807. PMID 15371550.
- Kaul-Ghanekar R, Majumdar S, Jalota A; et al. (2005). "Abnormal V(D)J recombination of T cell receptor beta locus in SMAR1 transgenic mice". J. Biol. Chem. 280 (10): 9450–9. doi:10.1074/jbc.M412206200. PMID 15623522.
- Jalota A, Singh K, Pavithra L; et al. (2005). "Tumor suppressor SMAR1 activates and stabilizes p53 through its arginine-serine-rich motif". J. Biol. Chem. 280 (16): 16019–29. doi:10.1074/jbc.M413200200. PMID 15701641.
- Rampalli S, Pavithra L, Bhatt A; et al. (2005). "Tumor suppressor SMAR1 mediates cyclin D1 repression by recruitment of the SIN3/histone deacetylase 1 complex". Mol. Cell. Biol. 25 (19): 8415–29. doi:10.1128/MCB.25.19.8415-8429.2005. PMID 16166625.
- Rual JF, Venkatesan K, Hao T; et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
- Kimura K, Wakamatsu A, Suzuki Y; et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMID 16344560.
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